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Solid-phase oxoalkylation of pyridines and quinolines with 1-methylcycloalkanols under the action of lead tetraacetate
Authors:Nikishin  G. I.  Sokova  L. L.  Kapustina  N. I.
Affiliation:(1) Russian Academy of Sciences, N. D. Zelinsky Institute of Organic Chemistry, 47 Leninsky prosp., 119991 Moscow, Russian Federation
Abstract:A new procedure was developed for the introduction of the oxoalkyl fragment into N-heteroaromatic compounds of the pyridine and quinoline series. The procedure is based on the solid-phase reactions of lead tetraacetate with aromatic N-heterocycles and tertiary cycloalkanols.
Keywords:N-heteroaromatic compounds  oxidative decyclization  oxoalkyl-substituted N-heterocycles  solid-phase oxoalkylation  lead tetraacetate  tertiary cycloalkanols
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