Dendritic folate rosettes as ion channels in lipid bilayers |
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Authors: | Sakai Naomi Kamikawa Yuko Nishii Masayuki Matsuoka Toru Kato Takashi Matile Stefan |
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Affiliation: | Department of Organic Chemistry, University of Geneva, Geneva, Switzerland. naomi.sakai@chiorg.unige.ch |
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Abstract: | The self-assembly of folate dendrimers into pi-stacked supramolecular rosettes is shown to produce ion channels in planar and spherical lipid bilayer membranes. The found ion channels are small, quite homogeneous, long-lived, ohmic, cation selective (Eisenman I), and blockable by the permeant cation. |
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