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Two New Diterpenoids and other Constituents from Isodon Nervosus
Authors:Fu‐Lin Yan  Lan‐Qing Guo  Su‐Ping Bai  Han‐Dong Sun
Affiliation:1. Pharmacy College, Xinxiang Medical University, Xinxiang 453003, P. R. China;2. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
Abstract:Two new ent‐kaurane diterpenoids, 15β‐hydroxy‐6,7‐seco‐6,11β:6,20‐diepoxy‐1α,7‐olide‐ent‐kaur‐16‐ene ( 1 ), 11α,15α‐dihydroxy‐6β‐methoxy‐6,7‐seco‐6,20‐epoxy‐1α,7‐olide‐ent‐kaur‐16‐ene ( 2 ), together with four known diterpenoids, nodosin ( 3 ), isodocarpin ( 4 ), odonicin ( 5 ) and maoyecrystal F ( 6 ) were isolated from the aerial parts of Isodon nervosus. The structures of the new compounds were elucidated on the basis of their spectral evidence, especially on 2D NMR.
Keywords:Labiatae  Isodon nervosus  ent‐Kaurane diterpenoid
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