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Three New Sesquiterpenoids from Xylaria sp. NCY2
Authors:Zhi‐Yu Hu  Yao‐Yao Li  Yao‐Jian Huang  Wen‐Jin Su  Yue‐Mao Shen
Institution:1. Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering;2. Xiamen Engineering Research Center of Marine Microbial Drug Discovery;3. Fujian Laboratory of Pharmaceutical Engineering;4. School of Life Sciences, Xiamen University, No. 422 South Siming Road, Xiamen, Fujian 361005, P.?R. China (phone: +86‐592‐2184180;5. fax: +86‐592‐2181772)
Abstract:Three new sesquiterpenoids, xylarenones A ( 1 ) and B ( 2 ), and xylarenic acid ( 3 ), were obtained from the endophytic fungal strain Xylaria sp. NCY2, which was isolated from Torreya jackii Chun . Their structures were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments, and by HR‐Q‐TOF mass spectrometry. The antitumor and antibacterial properties of the new compounds were evaluated.
Keywords:Xylaria sp  NCY2  Sesquiterpenoids  Xylarenones A and B  Xylarenic acid
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