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A Novel Method for the Synthesis of 4(3H)‐Quinazolinones
Authors:Xiao‐Bi Jing  Zhen Li  Xin Pan  Yao‐Cheng Shi
Abstract:Different metal perchlorates were screened to catalyze the three‐component reaction of anthranilic acid, triethyl orthoformate and amines to afford quinazolin‐4(3H)‐ones in solvent‐free conditions. Ni(ClO4)2 or Zn(ClO4)2 was demonstrated to be efficient to catalyze the reaction.
Keywords:Perchlorates  Quinazolin‐4(3H)‐ones  Amine  One‐pot reaction
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