Three New Arylnaphthalide Lignans from the Aerial Parts of Bupleurum marginatum Wall. ex DC. |
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Authors: | Ying Liu Ting‐Ting Zhang Jin‐Song Zhou Qiang Wang |
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Institution: | 1. Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Shennong Road 1, Nanjing 210038, P.?R. China, (phone: +86‐25‐85391253;2. fax: +86‐25‐85301528) |
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Abstract: | Three new arylnaphthalide lignans, 5‐(4‐hydroxy‐3‐methoxyphenyl)furo3′,4′: 6,7]naphtho2,3‐d]‐1,3‐dioxol‐6(8H)‐one ( 1 ), 10‐(4‐hydroxy‐3‐methoxyphenyl)furo3′,4′: 6,7]naphtho1,2‐d]‐1,3‐dioxol‐9(7H)‐one ( 2 ), and 10‐(3,4‐dimethoxyphenyl)‐6‐hydroxyfuro3′,4′: 6,7]naphtho1,2‐d]‐1,3‐dioxol‐9(7H)‐one ( 3 ), together with two known ones, chinensin ( 4 ) and isodiphyllin ( 5 ), were isolated from the aerial parts of Bupleurum marginatum Wall . ex DC. The structures of the three new lignans were established by means of NMR spectroscopic studies, including HQSC, HMBC, and ROESY. |
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Keywords: | Bupleurum marginatum Arylnaphthalide lignans Lignans |
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