Efficient Synthesis of Functionalized Thiazoles from Acid Chlorides,Tetramethylthiourea, Ethyl Bromopyruvate,and Ammonium Thiocyanate |
| |
| Authors: | Issa Yavari Zinatossadat Hossaini Samereh Seyfi Faezeh Shirgahi‐Talari |
| |
| Affiliation: | 1. Chemistry Department, Tarbiat Modares University, P.O. Box 14115‐175, Tehran, Iran, (phone: +98‐21‐82883465;2. fax: +98‐21‐82886544) |
| |
| Abstract: | An efficient synthesis of ethyl 2‐(dimethylamino)‐1,3‐thiazole‐4‐carboxylates is described via a four‐component reaction between acid chlorides, tetramethylthiourea, ethyl bromopyruvate, and ammonium thiocyanate. |
| |
| Keywords: | 1,3‐Thiazole‐4‐carboxylates Multicomponent synthesis |
|
|
