A New Triterpene and New Sesquiterpenes from the Roots of Ligularia sagitta |
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| Authors: | Ping‐Lin Li Zhong‐Jian Jia |
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| Institution: | 1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P.?R. China, (phone: +86‐931‐8912408, +86‐931‐8911136;2. fax: +86‐931‐8912582) |
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| Abstract: | One new triterpene and seven new eremophilane‐type sesquiterpenes were isolated from the roots of Ligularia sagitta, among them 1a , an O‐acetylated oleanane type triterpene, 2a and 3a , two 11‐nor eremophilane‐type sesquiterpenes, 4a, 5 , and 6 , three standard eremophilane‐type sesquiterpenes, and 7 and 8 , two tri‐nor eremophilane‐type sesquiterpenes. Their structures were established by extensive spectral analyses (1D, 2D‐NMR, IR, and MS). Compound 1a showed moderate cytotoxicity against two tumor cell lines. |
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| Keywords: | Ligularia sagitta Triterpenes Sesquiterpenes Oleananes Eremophilanes |
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