Baimantuoluolines D – F,Three New Withanolides from the Flower of Datura metel L. |
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| Authors: | Bingyou Yang Qiuhong Wang Yonggang Xia Weisheng Feng Haixue Kuang |
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| Affiliation: | 1. Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin 150040, P.?R. China, (phone: +8645182193001;2. fax: +8645182110803) |
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| Abstract: | Three new withanolide compounds, named baimantuoluolines D–F, along with three known withanolides and a lignan were isolated from the flower of Datura metel L., the parts effective against psoriasis. The structures of the new compounds were elucidated as (5α,6β,12β,20R,22R,24R,25S)‐21,24‐epoxy‐5,6,12‐trihydroxy‐27‐methoxy‐1‐oxowith‐2‐enolide ( 1 ), (5α,6β,12β,20R,22R,24R,25S)‐21,24‐epoxy‐5,6,12,27‐tetrahydroxy‐1‐oxowith‐2‐enolide ( 2 ), and (5α,6β,12β,22R)‐5,6,12,21‐tetrahydroxy‐1‐oxowith‐24‐enolide( 3 ) on the basis of physicochemical evidence. |
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| Keywords: | Datura metel Withanolides Baimantuoluolines D – F |
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