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Two New Nitrone Alkaloids from Huperzia serrata
Authors:Wen‐Yun Gao  Yi‐Ming Li  Shan‐Hao Jiang  Da‐Yuan Zhu
Affiliation:1. Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, P.?R. China, (phone: +86‐29‐88302427;2. fax: +86‐29‐88303551);3. State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201213, P.?R. China, (phone/fax: +86‐21‐50806728)
Abstract:Two new nitrone alkaloids were isolated from the whole plant of Huperzia serrata (Thunb .) Trev . They are both phlegmarine‐type lycopodium alkaloids with a nitrone moiety. Their structures were elucidated on the basis of spectral evidences, and their configurations were established on the basis of optical rotation, CD, and NOESY‐NMR data.
Keywords:Huperzia serrata  Phlegmarine  Alkaloids  Huperzines M and N  Nitrone alkaloids  Lycopodium alkaloids
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