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Additional Minor Phytoecdysteroids of Serratula wolffii
Authors:András Simon  Erika Liktor‐Busa  Gábor Tóth  Zoltán Kele  Judit Groska  Mária Báthori
Affiliation:1. Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szt. Gellért tér 4, HU‐1111 Budapest;2. Department of Pharmacognosy, University of Szeged, E?tv?s utca 6, HU‐6720 Szeged, (phone:?0036‐62‐545558;3. fax:?0036‐62‐545704);4. Department of Medical Chemistry, University of Szeged, Dóm tér 8, HU‐6720 Szeged
Abstract:Three new and one known ecdysteroids were identified in the MeOH extract of the roots of Serratula wolffii. The new compounds isolated were (11α)‐11‐hydroxyshidasterone ( 1 ), (2β,3α,5β,14β,22R)‐2,3,20,22,25‐pentahydroxycholest‐7‐en‐6‐one ( 2 ), and (2β,3α,5β,22R)‐2,3,20,22,25‐pentahydroxycholest‐7‐en‐6‐one ( 3 ), together with the known ponasterone A ( 4 ). This latter compound was now better characterized than earlier. The structures of compounds 1 – 4 were established by extensive spectroscopic techniques, including one‐ and two‐dimensional NMR methods.
Keywords:Serratula wolffii  Ecdysteroids  Phytoecdysteroids  Steroids
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