Three New Lanostane Triterpenoids,Inonotsutriols A,B, and C,from Inonotus obliquus |
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Authors: | Sayaka Taji Takeshi Yamada Reiko Tanaka |
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Affiliation: | 1. Department of Medicinal Chemistry, Osaka University of Pharmaceutical Sciences, 4‐20‐1 Nasahara, Takatsuki, Osaka 569‐1094, Japan, (phone: +81‐72‐690‐1084;2. fax: +81‐72‐690‐1084) |
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Abstract: | Three new lanostane‐type triterpenoids, inonotsutriols A ( 1 ), B ( 2 ), and C ( 3 ) were isolated from the sclerotia of Inonotus obliquus (Pers .: Fr.) (Japanese name: kabanoanatake; Russian name: chaga). Their structures were determined to be (3β,21R,24S)‐21,24‐cyclolanost‐8‐ene‐3,21,25‐triol ( 1 ), (3β,21R,24R)‐21,24‐cyclolanost‐8‐ene‐3,21,25‐triol ( 2 ), and (3β,21R,24S)‐21,24‐cyclolanosta‐7,9(11)‐diene‐3,21,25‐triol ( 3 ) on the basis of NMR spectroscopy including 1D and 2D experiments (1H,1H‐COSY, NOESY, HMQC, and HMBC) and EI‐MS. |
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Keywords: | Inonotus obliquus Triterpenoids Lanostane triterpenoids Inonotsutriols A – C |
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