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N‐Arylation of N‐H heterocycles with aryl bromides and aryl iodides using cui and kf/Al2O3
Authors:Rahman Hosseinzadeh  Mahmood Tajbakhsh  Mohammad Alikarami  Maryam Mohadjerani
Institution:1. Faculty of Chemistry, Department of Organic Chemistry, Mazandaran University, Babolsar, Iran;2. Islamic Azad University, Ilam, Iran;3. Faculty of Basic Science, Department of Biology, Mazandaran University, Babolsar, Iran
Abstract: chemical structure image Copper‐catalyzed system for N‐arylation of N‐H group in heterocycles such as indole, pyrrole and carbazole with aryl iodides and aryl bromides using potassium fluoride supported on alumina as a base is described. This is a simple and efficient method for the coupling of aryl iodides and bromides with N‐H heterocycles. Different functionalized iodo and bromo arenes were coupled with N‐H heterocycles using this system.
Keywords:
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