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Dowex as Reusable Acidic Polymeric Catalyst in the Efficient and Regioselective Conversion of Epoxides into β‐Hydroxy Thiocyanates under Solvent Free Conditions
Authors:Ali Reza Kiasat  Mehdi Fallah‐Mehrjardi
Affiliation:Department of Chemistry, Faculty of Sciences, Shahid Chamran University, Ahvaz 61357‐4‐3169, Iran
Abstract:A convenient and efficient procedure for the regioselective ring opening of epoxides in the presence of Dowex (strongly acidic cationic exchange resin), as reusable eco‐friendly catalyst under solvent free conditions is described. Thus, several β‐hydroxy thiocyanates, useful intermediates toward pharmaceutical and biologically active molecules, are easily obtained in high isolated yields.
Keywords:Dowex  Epoxide  β  ‐Hydroxy thiocyanate  Solvent free  Ring opening
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