New Components Including Cyclopeptides from Barks of Christiana africana DC. (Tiliaceae) |
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| Authors: | Serge Michalet Laëtitia Payen‐Fattaccioli Chantal Beney Pascale Cégiéla Christine Bayet Gilbert Cartier Diderot Noungoué‐Tchamo Etienne Tsamo Anne‐Marie Mariotte Marie‐Geneviève Dijoux‐Franca |
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| Institution: | 1. Laboratoire de Pharmacognosie, Département de Pharmacochimie Moléculaire, UMR 5063, CNRS‐UJF, UFR de Pharmacie de Grenoble I, Domaine de la Merci, F‐38706 La Tronche cedex (phone: +33 (0)478777052;2. fax: +33 (0)478777565);3. Université de Lyon, UMR CNRS 5557‐Ecologie Microbienne, ISPB, 8 avenue Rockefeller, F‐69373 Lyon cedex 08;4. Laboratory of Organic Chemistry, Faculty of Sciences, University of Yaoundé I, Yaoundé, Cameroon;5. New address: UMR CNRS 5557, Univ. de Lyon (Lyon 1, Claude Bernard), ISPB, Dépt. Botanique et Pharmacognosie, 8 Av. Rockefeller, F‐69373 Lyon cedex 08. |
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| Abstract: | Phytochemical investigation of barks of Christiana africana led to the identification of cyclopeptide alkaloids, flavonoids, coumarinolignans, iridoids, sesquiterpenoids, and triterpenes. This plant was classified so far in the Tiliaceae family. This study was started while the genomic study of numerous specimens was described in order to establish new criteria for Malvales botanical classification. In the present work, twenty components were identified, belonging to the three major classes of secondary metabolites: alkaloids, phenols, and terpenes. In the first class, cyclopeptides are well‐known compounds in Rhamnaceae and Sterculiaceae. Their presence in Malvaceae (in APG2 sensus) suggests a possible chemical link between the ex‐Tiliaceae and the Malvaceae. |
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| Keywords: | Christiana africana Cyclopeptides Phenylpropanoids Coumarinolignans Iridoids Sesquiterpenoids Triterpenoids Alkaloids Lignans Guainone |
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