1. Faculty of Chemistry, Tarbiat Moallem University, Mofatteh Ave., No 49, Postal Code 15614, Tehran, Iran;2. Department of Chemistry, Payame Noor University, Qazvin, Iran Tel.: 0098‐21‐8832920;3. Fax: 0098‐21‐88825580
Abstract:
Novel symmetrical bis‐Schiff bases have been prepared cleanly and efficiently in the presence of formic acid catalyst in methanol from the reaction of symmetrical primary bis‐amine of 5,5′‐methylenebis(2‐aminothiazole) ( 1 ) and a series of aromatic aldehyde derivatives under mild conditions. The advantages of this reaction are simplicity of the reaction procedure, simple work‐up and pure products with high yields. The structures of all the new synthesized symmetrical bis‐Schiff bases were confirmed by elemental analyses, IR, 1H‐NMR, 13C‐NMR and mass spectra.
