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Regioselective three‐component synthesis of novel indeno[1,2‐b]‐pyrazolo[4,3‐e]pyridines‐fused derivatives of 4‐azafluorenone alkaloid
Authors:Jairo Quiroga  Débora Cobo  Braulio Insuasty  Rodrigo Abonía  Silvia Cruz  Manuel Nogueras  Justo Cobo
Affiliation:1. Grupo de Investigación de Compuestos Heterocíclicos, Department of Chemistry, Universidad del Valle, A. A. 25360, Cali, Colombia;2. Department of Chemistry, Universidad de Nari?o, A.A. 1175, Pasto‐Colombia;3. Department of Inorganic and Organic Chemistry, Universidad de Jaén, 23071 Jaén, Spain
Abstract: chemical structure image New fused indeno[1,2‐b]pyridine derivatives have been prepared in a multicomponent reaction from benzaldehydes, indanedione and the appropriate aminoheteroaryl compound. The simple methodology permitted the syntheses of a series of indeno[1,2‐b]pyrazolo[4,3‐e]pyridines 4 from 5‐aminopyrazol 1 and modulated by the corresponding benzaldehyde 2 .
Keywords:
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