Two New Steroidal Alkaloids from Veratrum nigrum L. |
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| Authors: | Bin Wang Wei‐Dong Zhang Yun‐Heng Shen Jian Tang Chuan Zhang Run‐hui Liu Min Lin Hui‐Liang Li |
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| Institution: | 1. Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, P.?R. China (phone: +86‐21‐25070387;2. fax: +86‐21‐25070387);3. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200030, P.?R. China |
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| Abstract: | Phytochemical studies on Veratrum nigrum L., collected in Shanxi, P. R. China, resulted in the isolation of two new steroidal alkaloids, 23‐methoxycyclopamine ( 1 ) and 15‐O‐(2‐methylbutanoyl)‐3‐O‐veratroylprotoverine ( 2 ). The structures of the two new compounds were established by means of extensive NMR spectroscopic studies. |
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| Keywords: | Veratrum nigrum Steroidal alkaloids Alkaloids Cyclopamine 23‐methoxy‐ Protoverine 15‐O‐(2‐methylbutanoyl)‐3‐O‐veratroyl‐ |
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