1. UMR 6180 CNRS and Université d'Aix‐Marseille III: “Chirotechnologies: catalyse et biocatalyse”, Laboratoire de Synthèse Organique, Faculté des Sciences de Saint Jér?me, Université d'Aix‐Marseille III, Avenue Escadrille Normandie‐Niemen, 13397 Marseille Cedex 20, France;2. 02–23–23–62–8002–23–23–69–39;3. Institut Sciences Chimiques de Rennes, UMR 6226 CNRS‐Université de Rennes “Catalyse et Organometalliques”, Campus de Beaulieu, 35042 Rennes, France;4. (33) 4 91 98 91 12
Abstract:
cis,cis,cis‐1,2,3,4‐Tetrakis(diphenylphosphinomethyl)cyclopentane/PdCl(C3H5)]2 efficiently catalyses the Suzuki reaction of heteroarylboronic acids with aryl bromides and also the coupling of arylboronic acids with heteroaryl bromides. The coupling of thiophene‐ or benzothiopheneboronic acids, furan‐ or benzofuranboronic acids and 3‐pyridineboronic acid with a variety of aryl bromides gave the corresponding coupling products in good yields. However, in most cases, better results in terms of ratio substrate/catalyst were obtained for the reverse reaction using heteroaryl bromides with arylboronic acids.
