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Sequence‐Specific Positions of Water Molecules at the Interface between DNA and Minor Groove Binders |
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| Authors: | Gudrun M. Spitzer Julian E. Fuchs Patrick Markt Dr. Johannes Kirchmair Dr. Bernd Wellenzohn Dr. Thierry Langer Prof. Klaus R. Liedl Prof. |
| Affiliation: | 1. Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A‐6020 Innsbruck (Austria), Fax: (+43)?512‐507‐2714;2. CAMD Group, Institute of Pharmacy, University of Innsbruck, Innrain 52c, A‐6020 Innsbruck (Austria);3. Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Strasse 65,D‐88397 Biberach/Riss (Germany);4. Prestwick Chemicals, Inc., Boulevard Gonthier d'Andernach, Parc d'Innovation, 67400 Illkirch (France) |
| Abstract: | |
| Keywords: | DNA recognition drug design hydrogen bonds ligands solvent effects |