Cerium(IV) ammonium nitrate catalyzed green synthesis of 2-substituted 2,3-dihydro- quinazolin-4(1H)-ones using a grinding technique |
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| Authors: | M. Wang J. J. Gao Z. G. Song L. Wang |
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| Affiliation: | (1) College of Chemistry, Chemical Engineering and Food Safety, Bohai University, Jinzhou, 121000, P. R. China;(2) Center for Science & Technology Experiment, Bohai University, Jinzhou, 121000, P. R. China |
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| Abstract: | An efficient and facile method for the synthesis of 2-substituted 2,3-dihydro-quinazolin-4(1H)-ones from anthranilamide with aldehydes or ketones in the presence of cerium(IV) ammonium nitrate in water by a grinding technique has been developed. The structures of the new products were proved by IR, 1H NMR, MS, and elemental analysis. A plausible mechanism for the formation of these products is proposed. |
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