| Abstract: | A sequence of conversions including 1,3-dipolar cycloaddition of nitrile oxides to steroid 22-enes and modification of the isoxazolines obtained by hydroxylation to the 4′ position and splitting of the heterocycle leads to steroids with a polyfunctional open chain, 22,23-dihydroxy 24-ketones. For preliminary report see [1]. Institute of Bioorganic Chemistry, Academy of Sciences of Belarus', Minsk 220141. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 542–548, April, 1997. |
