| 葛根素-7-磷酸二乙酯的NMR研究 |
| |
| 引用本文： | 袁金伟,陈晓岚,汪茂田,屈凌波,赵玉芬. 葛根素-7-磷酸二乙酯的NMR研究[J]. 波谱学杂志, 2005, 22(4): 409-414 |
| |
| 作者姓名： | 袁金伟 陈晓岚 汪茂田 屈凌波 赵玉芬 |
| |
| 作者单位： | 河南省化学生物与有机化学重点实验室，郑州大学化 学系，河南 郑州 450052 |
| |
| 基金项目： | 中国科学院资助项目，河南省杰出青年科学基金 |
| |
| 摘 要： | 葛根素是从常用中药野葛根中分离提取出来的一种具有很强生物活性的异黄酮碳苷类化合物，设计并合成了一种新的化合物葛根素-7-磷酸二乙酯. 在常温下，这种新的化合物在NMR谱上有两组相关的信号峰，即在溶液中以两种不同的构象存在. 本文利用HSQC和HMBC等多种二维核磁共振技术对这种化合物的NMR谱进行了全归属.
|
| 关 键 词： | NMR 全归属 2D NMR 葛根素-7-磷酸二乙基酯 |
| 文章编号： | 1000-4556（2005）04-0409-07 |
| 收稿时间： | 2005-05-11 |
| 修稿时间： | 2005-07-06 |
Synthesis and NMR Characterization of Diethyl Puerarin-7-yl Phosphate |
| |
| YUAN Jin-wei,CHEN Xiao-lan,WANG Mao-tian,QU Ling-bo,ZHAO Yu-fen. Synthesis and NMR Characterization of Diethyl Puerarin-7-yl Phosphate[J]. Chinese Journal of Magnetic Resonance, 2005, 22(4): 409-414 |
| |
| Authors: | YUAN Jin-wei CHEN Xiao-lan WANG Mao-tian QU Ling-bo ZHAO Yu-fen |
| |
| Affiliation: | Henan Provincial Key Laboratory of Bio- Chemistry and Organic Chemistry, Department of Chemistry, Zhengzhou University, Zhengzhou 450052, China |
| |
| Abstract: | Puerarin,an isoflavone compound,is the bioactive component of traditional Chinese medicine puerarin lobate(wild).A novel diethyl puerarin-7-yl phosphate was synthesized by the Atherton-Todd reaction with high productive yield.It was found that the compound synthesized has two sets of NMR signals at room temperature,suggesting the existence of two conformational isomers in solution.The1H chemical shifts of the compound were assigned using two-dimensional NMR techniques,including1H-detected heteronuclear multiple-quantum coherence and1H-detected multiple-bond heteronuclear multiple-quantum coherence. |
| |
| Keywords: | NMR 2D NMR |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
|
点击此处可从《波谱学杂志》下载全文 |
