Improvement of spectral resolution by spectroscopic imaging |
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Authors: | I Serša S Macura |
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Institution: | 1. Department of Condensed Matter Physics, Jo?ef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia 2. Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
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Abstract: | We propose to use three-dimensional spectroscopic imaging (SI) to increase the spectral resolution for biological samples for which strong susceptibility effects (or poor magnetic homogeneity) cause significant line broadening. Due to susceptibility effects (or poor field homogeneity) the SI voxel spectra even from a uniform sample are shifted with respect to each other and much less broadened than the total sample spectrum. Realignment of the spectra from individual voxels prior to their coaddition produces a total-volume spectrum with significantly narrower lines. |
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