Pyrophosphate tetraester intermediate of coupling reactions in the phosphotriester approach to the synthesis of deoxyligoribonucleotides |
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| Authors: | EM Ivanova LM Khalimskaya VP Romanenko VF Zarytova |
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| Institution: | Institute of Organic Chemistry, Siberian Division of the Academy of Sciences of the USSr, Novosibirsk, 630090, USSR |
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| Abstract: | The intermediate in phosphotriester formation in the presence of ARSO2Cl, ArSO2Tet, ArSO2NT and mixtures of ArSO2Cl + Tet (Nt, MeIm, DMAP) was established to be pyrophosphate tetraester II. |
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