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A convenient synthesis of 6-, 7-, and 8-membered cyclic phosphodiesters
Authors:Fausto Ramirez  Hikotada Tsuboi  Hiroshi Okazaki  James F Marecek
Institution:Department of Chemistry, State University of New York at Stony Brook Stony Brook, New York 11794, USA
Abstract:1,3-, 1,4-, and 1,5-Alkanediols are converted into the corresponding 6-, 7-, and 8- membered cyclic phosphodiesters in a two-step procedure utilizing N-(1,2-dimethylethylene-dioxyphosphoryl)imidazole (2? as the sole phosphorylating reagent.
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