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Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules |
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| Authors: | Hanif Muhammad Nazarov Alexey A Legin Anton Groessl Michael Arion Vladimir B Jakupec Michael A Tsybin Yury O Dyson Paul J Keppler Bernhard K Hartinger Christian G |
| Institution: | University of Vienna, Institute of Inorganic Chemistry, Waehringer Str. 42, A-1090 Vienna, Austria. |
| Abstract: | Ru(II)(arene) anticancer compounds with maleimide functionality were prepared to allow selective interaction with thiol-containing biomolecules and thereby enforcing the selective delivery of the compounds to the tumour. |
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