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A new dihydroisocoumarin from the strain Aspergillus sp. CMM, an endophytic fungus of Cephalotaxus mannii
Authors:Chunhua Lu  Xiang Lin  Yuemao Shen
Institution:(1) Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, Xiamen Engineering Research Center of Marine Microbial Drug Discovery; Fujian Laboratory of Pharmaceutical Engineering; School of Life Science, Xiamen University, Xiamen, Fujian, 361005, P. R. China
Abstract:From the branch tissue of Cephalotaxus mannii, the endophytic fungal strain CMM was isolated and determined to belong to the genus Aspergillus according to its internal transcribed spacer (ITS) sequence of rDNA (ITS1-5.8S-ITS2). From the extracts of the fermentation broth of CMM, a new compound, namely 5-O-α-D-glucopyranosyl-5-hydroxymellein (1), was isolated, together with a known compound 4-hydroxymellein (2). Their structures were elucidated on the basis of 1D and 2D NMR data. Published in Khimiya Prirodnykh Soedinenii, No. 5, pp. 461–462, September-October, 2008.
Keywords:Cephalotaxus mannii            5-O-α  -D-glucopyranosyl-5-hydroxymellein  4-hydroxymellein
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