Determination of DEHP in blood products stored in plastic bags by HPLC |
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| Authors: | I Gerlai J Pintér J Pick |
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| Institution: | (1) National Institute of Haematology and Blood Transfusion, P.O. Box 44, H-1502 Budapest, Hungary;(2) Institute of Experimental Medicine of the Hungarian Acad. Sci., P.O. Box 67, H-1450 Budapest, Hungary |
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| Abstract: | Summary High-performance liquid chromatography (HPLC) was used for the routine monitoring of the plasticizers di(2-ethylhexyl) phthalate
(DEHP) and tri(2-ethylhexyl) trimellitate (TOTM), in blood products. It allows easy sample clean-up, solvent extraction using
Celite 545 sorbent, good recoveries and opportunity to inject large number of samples without effect on column performance.
The plasticizer levels were investigated in two types of poly(vinyl chloride) (PVC) bags containing whole blood plasma, platelet
concentrates (PCs) during blood taking and storage. |
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| Keywords: | Column liquid chromatography Di(2-ethylhexyl) phthalate Tri(2-ethylhexyl) trimellitate Plasticizers Blood product storage |
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