| SOD、MDA在自身免疫性甲状腺疾病患者血清中的变化及其与尿碘的关系研究 |
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| 引用本文： | 丛建妮,赵拥军,李革.SOD、MDA在自身免疫性甲状腺疾病患者血清中的变化及其与尿碘的关系研究[J].广东微量元素科学,2011,18(8):12-15. |
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| 作者姓名： | 丛建妮 赵拥军 李革 |
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| 作者单位： | 1. 山东省滨州医学院,山东,烟台,264003
2. 重庆医科大学,重庆,630000 |
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| 基金项目： | 重庆市“十一五”科技发展规划重大专项(CSTC,2007AB5034) |
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| 摘 要： | 为了解重庆地区自身免疫性甲状腺疾病(AITD)患者体内SOD、MDA的变化情况及其与尿碘的关系,初步探讨碘在AITD发病中的作用机制,采用病例对照研究,检测并分析了各组人群外周血SOD、MDA及尿碘的含量.结果表明:(1)GD与HT组尿碘中位数高于对照组(P<0.000 1);(2)GD与HT患者血清中的MDA含量高于...
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| 关 键 词： | 自身免疫性甲状腺疾病 Graves病(GD) 桥本甲状腺炎(HT) 超氧化物歧化酶 丙二醛 尿碘 |
The Changes of SOD,MDA in Serum of Patients with Autoimmune Thyroid Disease and Its Relationship with Urinary Iodine |
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| CONG Jianni,ZHAO Yongjun,LI Ge.The Changes of SOD,MDA in Serum of Patients with Autoimmune Thyroid Disease and Its Relationship with Urinary Iodine[J].Trace Elements Science,2011,18(8):12-15. |
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| Authors: | CONG Jianni ZHAO Yongjun LI Ge |
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| Institution: | CONG Jianni1,ZHAO Yongjun1,LI Ge2(1.Binzhou Medical University,Shandong Yantai,264003,China,2.Chongqing University of Medical Sciences,Chongqi,630000,China) |
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| Abstract: | To know the relationship of SOD,MDA with urinary iodine in Chongqing and its changes in the serum of patients with autoimmune thyroid disease,and to discuss preliminarily the effect of iodine in the mechanism of the pathogenesis of AITD,taking a case-control study,SOD,MDA and urine iodine levels were detected in each group.The results showed that(1)The median urinary iodine of GD and HT was higher than control group(P<0.000 1);(2)The content of MDA of GD and HT was higher than control group,n(SOD)/c(MDA) ra... |
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| Keywords: | autoimmune thyroid diseases(AITD) Graves disease(GD) Hashimoto's thyroiditis(HT) SOD MDA urinary iodine |
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