Solid-Phase Luminescence Determination of Ciprofloxacin and Norfloxacin in Biological Fluids |
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| Authors: | Svetlana Beltyukova Olga Teslyuk Alla Egorova Elena Tselik |
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| Institution: | (1) Odessa's State Academy of Food Technologies, 112, Kanatnaya St., Odessa, Ukraine;(2) A. V. Bogatsky Physico-chemical Institute, National Academy of Sciences of Ukraine, 86, Lustdorfskaya doroga, Odessa, 65080, Ukraine |
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| Abstract: | A simple, rapid, and sensitive luminescence test method for the determination of ciprofloxacin (CIP) and norfloxacin (NOR) has been described. The method is based on the intramolecular energy transfer from organic acid to terbium (Tb3+) ion. Luminescence of terbium (III) complex with CIP (NOR), sorbed on the zeolite has been studied. Under optimized conditions the detection limit is 1  g/mL in urine and human plasma. |
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| Keywords: | Sensitized luminescence ciprofloxacin norfloxacin zeolite terbium (III) ion drug analysis |
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