Hyaluronidase inhibitory rosmarinic acid derivatives from Meehania urticifolia |
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| Authors: | Murata Toshihiro Miyase Toshio Yoshizaki Fumihiko |
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| Institution: | Department of Pharmacognosy, Tohoku Pharmaceutical University, Aoba-ku, Sendai, Japan. murata-t@tohoku-pharm.ac.jp |
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| Abstract: | Nine new phenylpropanoids, rashomonic acids A-D (1-4) and meehaniosides A-E (5-9), along with four known compounds were isolated from Meehania urticifolia. The structure of each new compound was elucidated based on the results of spectroscopic analyses. Compounds 3-8 showed moderate hyaluronidase inhibitory activity with IC(50) values of 183-1049 μM. |
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