Immunoenzyme assay for the determination of prostatic acid phosphatase in plasma samples |
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Authors: | K. P. Kohse, G. Pfleiderer, S. H. Flü chter K. -H. Bidder |
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Affiliation: | (1) Zentrum für Innere Medizin, Sektion Nephrologie, Klinikum der Universität Ulm, Steinhövelstraße 1, D-7900 Ulm;(2) Institut für Organische Chemie, Biochemie und Isotopenforschung der Universität Stuttgart, Pfaffenwaldring 55, D-7000 Stuttgart 80;(3) Abteilung Urologie, Chirurgische Universitätsklinik, Calwer Straße 7, D-7400 Tübingen, Federal Republic of Germany |
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Abstract: | Conclusion The determination of PAP in plasma samples with the new IEA improves the analytical specifity and appears to be superior to the serum RIA method. It allows a clearer distinction of prostatic carcinoma patients, especially in earlier stages of the disease, from those with benign prostatic hyperplasia. Although it, too, certainly cannot be regarded as suitable for a general screening for prostatic cancer, it may serve as an useful additional aid in the diagnosis and therapy-monitoring of the disease.
Immunoenzymtest zur Bestimmung der prostataspezifischen sauren Phosphatase in Plasmaproben |
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