Mild synthesis of polyfunctional benzimidazoles and indoles by the reduction of functionalized nitroarenes with phenylmagnesium chloride |
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| Authors: | Dohle Wolfgang Staubitz Anne Knochel Paul |
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| Institution: | Department Chemie, Ludwig-Maximilians-Universit?t, Butenandtstrasse 5 - 13, Haus F, 81377 München, Germany. |
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| Abstract: | Phenylmagnesium chloride has been used for the conversion of selected nitroarenes into nitrenes. Their insertion into a neighboring sp(2) C-H bond yielded functionalized heterocycles. A novel and mild synthesis of polyfunctional benzimidazoles and indoles is described. |
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| Keywords: | Grignard reaction heterocycles magnesium nitrenoids nitrenes |
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