Synthesis and Crystal Structure of a Hydrogen-bonded Supramolecular Compound [(C_6H_5N_2O)_3·Cu_1._5]·6H_2O

1 INTRODUCTION The binding of metal ions by proteins and pep- tides is of fundamental interest due to the impor- tance of metal ions in biological systems. Metals may be part of the active sites of enzymes, stabilize the macromolecular structure of proteins and affect enzymes or membranes to control cell metabolism[1]. Therefore, for many years there has been a great in- terest in the study of complexes able to mimic these active sites of metalloproteins. In this case, metal complexes of…

Synthesis and Crystal Structure of a Hydrogen-bonded Supramolecular Compound [(C_6H_5N_2O)_3·Cu_1._5]·6H_2O

A hydrogen-bonded supermolecular compound [(C6H5N2O)3?Cu1.5]?6H2O was syn- thesized from picolinamide and Cu(NO3)2?6H2O at the presence of sodium pyrophosphate deca- hydrate. It crystallizes in triclinic, space group P1 with a = 1.05947(8), b = 1.09130(8), c = 1.11456(8) nm, α = 67.8460(10), β = 84.497(1), γ = 74.6210(10)o, C18H27Cu1.5N6O9, Mr = 566.77, V = 1.15077(15) nm3, Z = 2, Dc = 1.636 g/cm3, F(000) = 585, μ = 1.461 mm?1, R1 = 0.0278 and wR2 = 0.0749. In the complex, the Cu(II) ion reveals a distorted tetradentate plane-tetragonal geometry. The structure consists of neutral two-dimensional layers via hydrogen bonds O–H???O and N–H???O between the molecules, and the layers are connected by weak interactions of the Cu–Cu, Cu–N, π-π and hydrogen bonds to form a three-dimensional network structure.