长波敏化发光铕配合物纳米粒子的制备与表征

以牛血清白蛋白(BSA)为保护剂, 利用沉淀法制备了平均粒径为35 nm的Eu(tta)3dpbt (dpbt = 2-(N,N-二乙基苯胺-4-基)-4,6-二(3,5-二甲基吡唑-1-基)-1,3,5-三嗪, tta = 噻吩甲酰三氟丙酮负离子)荧光纳米粒子. BSA保护Eu(tta)3dpbt纳米粒子在水中分散稳定性高, 光稳定性好, 长波敏化发光性能优良. 其在可见光区激发峰位于415 nm, 激发峰尾部延展至470 nm, 发光量子产率为0.20 (λex=415 nm, 25 ℃). 在近红外双光子激发下可发出纯正的红光, Eu(tta)3dpbt纳米粒子最大双光子激发作用截面为2.4×10⁵ GM (λex=830 nm, 1 GM=10^-50 cm⁴·s·photo^-1·particle^-1).

Synthesis and Characterization of Europium Complex Nanoparticles with Long-Wavelength Sensitized Luminescence

Luminescent nanoparticles (dav=35 nm) of Eu(tta)3dpbt (dpbt= 2-(N,N-diethylanilin-4-yl)-4,6-bis (3,5-dimethylpyrazol-1-yl)-1,3,5-triazine, tta=thenoyltrifluoroacetonato) protected by bovine serum albumin (BSA) were prepared by a precipitation method. These particles disperse well in aqueous solutions to form stable and transparent colloidal solutions. The BSA-protected Eu(tta)3dpbt nanoparticles exhibit high photostability and excellent long-wavelength sensitized EuIII luminescence properties. The quantum yield of EuIII luminescence is 0.20 (λex=415 nm, 25 ℃), and the excitation band for the EuIII luminescence centers at 415 nm and extends to 470 nm. Upon two-photon excitation, the prepared nanoparticles emit pure-red light with a two-photon excitation action cross section of 2.4×10⁵ GM (λex=830 nm, 1 GM=10^-50 cm4·s·photo^-1·particle^-1). The prepared nanoparticles and the reported preparation method are promising for the development of luminescent bionanoprobes with excellent biocompatibility and luminescent properties.