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Water-soluble phosphonium salts containing 1,12-dicarba-closo-dodecaborane(12)
Authors:Joseph A. Ioppolo  Louis M. Rendina
Affiliation:a School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia
b Discipline of Medical Radiation Sciences, The University of Sydney, Sydney, NSW 2006, Australia
c Brain and Mind Research Institute, The University of Sydney, Sydney, NSW 2050, Australia
Abstract:The preparation of new water-soluble phosphonium salts containing 1,12-dodeca-closo-dodecaborane(12) (closo-1,12-carborane) for potential use as tumor-targeting agents in Boron Neutron Capture Therapy (BNCT) is described.
Keywords:Phosphonium salt   Carborane   Ethylene glycol   Hydrophilic   BNCT
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