Silver triflate and triphenylphosphine co-catalyzed reactions of 2-alkynylbenzaldehyde, amine, and α,β-unsaturated ketone |
| |
| Authors: | Shengqing Ye |
| |
| Affiliation: | a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China
b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China |
| |
| Abstract: | A two-component activation system that combines metal catalysis (AgOTf) and the employment of catalytic amount of organocatalyst (PPh3) has been successfully employed in the three-component reaction of 2-alkynylbenzaldehyde, amine, and α,β-unsaturated ketone. This reaction proceeds smoothly in THF under mild conditions leading to the functionalized 1,2-dihydroisoquinolines in moderate to good yields. |
| |
| Keywords: | 2-Alkynylbenzaldehyde Amine α,β-Unsaturated ketone 1,2-Dihydroisoquinoline Silver triflate Triphenylphosphine |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
