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Surface-enhanced Raman on gold nanoparticles for the identification of the most common adulterant of Astragali Radix |
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| Authors: | Hongxin Lin Ying Chen Shangyuan Feng Weiwei Chen Duo Lin Hao Huang |
| Institution: | 1. Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Normal University, Fujian, China;2. Provincial Clinical College of Fujian Medical University, Fujian, China;3. Fujian University of Traditional Chinese Medicine, Fujian, China |
| Abstract: | Adulterant is a common problem in Astragali Radix (a widely used Chinese herbal medicine). In this study, the surface-enhanced Raman technique was used to identify the authentic Astragali Radix and the most common adulterant with the aim to develop a convenient and sensitive method for the adulterant identification. Surface-enhanced Raman spectra combined with multivariate diagnostic algorithm differentiated the authentic Astragali Radix from the adulterant with high sensitivity (100%) and specificity (97.6%). This exploratory work demonstrates that surface-enhanced Raman technology can be used for the rapid and label-free screening of adulterant and has great potential for the quality control of Chinese herbal. |
| Keywords: | adulterant Astragali Radix multivariate algorithm surface-enhanced Raman scattering |