NMR and FT-Raman Studies on the Interaction of Lanthanide Ions with Sphingomyelin Bilayers |
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| Authors: | Chunbo Yuan Daqing Zhao Bing Zhao Jiazuan Ni |
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| Institution: | 1. National Laboratory of Molecular and Biomolecular Electronics, Department of Chemical Engineering &2. Chemistry, Southeast University , Nanjing, 210096, P. R. China;3. Laboratory of Rare Earth Chemistry &4. Physics , Changchun Institute of Applied Chemistry, Academica Sinica , Changchun, 130022, P. R. China;5. Key Laboratory of Molecular Spectra and Structure , Jilin University , Changchun, 130023, P. R. China |
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| Abstract: | The interactions of lanthanide ions with sphingomyelin bilayers have been studied by using 2D NOESY spectroscopy and FT-Raman spectroscopy methods. The results indicate that lanthanide ions, as well as divalent calcium, combine mainly to the phosphate group in the polar headgroup and do not change the conformation of O-C-C-N+ backbone in the choline group of sphingomyelin bilayers. The polar headgroup is still extending parallel to the bilayer surface and O-C-C-N+ group is still in its gauche conformer. |
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| Keywords: | NMR FT-Raman Sphingomyelin Bilayers Lanthanide ions |
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