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Study of the Proton Magnetic Resonance of Methoxy-Tamoxifen Towards Ortho-Substitution
Authors:Hoda A. El-Wakil
Affiliation:Department of Chemistry, Faculty of Science , Alexandria University , Alexandria, Egypt
Abstract:The objective of the work was to study the proton magnetic resonance of derivatives of methoxytamoxifen towards ortho substitution of a trialkylstannyl-moiety and iodine. Since Iodo-methoxytamoxifen was specially needed for further biological studies in the detection and characterisation of breast tumors, it was necessary to be certain of the position of substitution (i.e. ortho to the amino ether).
Keywords:The proton magnetic resonance of a series of compounds involved in the synthesis of Iodomethoxytamoxifen
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