FAB of peptides study: Deuterated glycerol matrix and selectively deuterated peptides. Part II |
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| Authors: | H Lam-tranh D Gaudin H Virelizier R Hagemann S Fermandjian K Jankowski |
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| Institution: | 1. CEN de Saclay , 91191 , Gif-Sur-Yvette , France;2. CEN de Saclay , 91191 , Gif-Sur-Yvette , France;3. Departinent of Chemistry , Universitd de Moncton , Moncton , N.B. , E1A 3E9 , Canada |
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| Abstract: | Abstract Two peptides, H-Gly-Lys-Thr-Gly-Pro-Gly-OH (1) and Leu-enkephalin (2) FAB-PI spectra in normal and deuterated glycerol have been studied. Two C-deuterated and D2O exchanged analogs have been used to compare their fragmentation to unlabelled peptides. The mass spectrometry of peptides has become a particularly interesting field with the wide spread adoption of the FAB technique. This technique enables one to record the quasi-molecular ion (in both positive and negative modes as M+1 or M?1 respectively) and to extract from the spectrum valuable information on the peptide sequence. |
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