PMR Assay of Essential Oils: II. Assay of Methylsalicylate in Wintergreen Oil |
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| Authors: | H. A. El-obeid M. M. A. Hassan |
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| Affiliation: | Dept. of Pharmaceutical Chemistry , College of Pharmacy, Riyad University , Riyad, Saudi Arabia |
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| Abstract: | An NMR procedure is described for the quantitative determination of methylsalicylate as a drug entity and in wintergreen oil. For standard mixtures containing the pure drug a mean result of 99.9 ± 0.75% w/w was obtained. Analysis of a wintergreen oil sample for its contents of methyl-salicylate gave a mean result of 99.2 ± 0.17% w/w. The results are compared with those obtained using the official procedure. |
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| Keywords: | Methylsalicylate, NMR Analysis NMR Analysis, Wintergreen Oil Salicylic acid, Methyl ester, NMR Analysis. |
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