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The Determination of Lactate or Acetate in Intravenous Infusions and Haemodialys1S Solutions by 1H NMR Spectroscopy
Authors:A. Mazzec Farina
Affiliation:Laboratory of Pharmaceutical Chemistry , Istituto Superiore di Sanità , 00161, Rome, Italy
Abstract:A 1H NMR spectroscopic determination for acetate and lactate in intravenous and haemodialysis solutions is reported. The methyl resonances of acetate and lactate were chosen for integration using N-methylurea and sodium acetate, respectively, as internal standards. The results obtained indicate that the quantitative measurements are reproducible. The method provides also a specific identification of the analytes.
Keywords:Quantitative PMR spectroscopy  acetate and lactate in intravenous Infusions and haemodialysis solutions
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