Comparison of NMR Water Proton T1 Measurements in Healthy and Pathological Blood |
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| Authors: | Ali Yilmaz Müjgan Tez Halil Degertekin |
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| Affiliation: | 1. Department of Physics , Faculty of Science, University of Dicle , Diyarbakir , Turkey;2. Department of Mathematics , Faculty of Science, University of Dicle , Diyarbakir , Turkey;3. Department of Internal Medicine , School of Medicine, University of Dicle , Diyarbakir , Turkey |
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| Abstract: | water proton T1 in blood from healthy volunteers and patients with acute leukaemia, lymphoma; iron deficiency anaemia, post hepatitic cirrhosis and tuberculosis, was measured by a FT-NMR spectrometer. Relaxation measurements were performed at 60MHz frequency and a temperature of (20 ± 0.5)C. The T1 measured for each disease correlates strongly with hemoglobin content. The spin-lattice relaxation time in each abnormal group was signaficantly (p < 0.001) elevated over normal group. There is little overlap between the healthy and abnormal groups. On the contrast, T1 ranges obtained for malignant groups and non-malignant diseases do overlap. |
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