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Determination of Diethylcarbamazine Citrate in Tablets by Proton Magnetic Resonance |
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| Authors: | Humeida A. El-obeid |
| Affiliation: | Department of Pharmaceutical Chemistry, College of Pharmacy , King Saud University , Riyadh, 11451, Saudi Arabia |
| Abstract: | A simple, specific and accurate proton magnetic resonance (PMR) procedure has been developed for the quantitative determination of diethylcarbamazine in standard mixtures and tablets. The average recovery of the pure drug in standard mixtures with maleic acid as an internal standard was 100.03 ± 0.11% w/w. Reproducible results were obtained when the drug was determined in its tablet dosage form. |
| Keywords: | PMR assay Carbamazine citrate in pharmaceutical dosage forms. NMR assay diethylcarbamazine citrate in pharmaceutical dosage forms. Hetrazan PMR assay in pharmaceutical dosage forms. |