2,6-Dialkoxy-7-methylpurines |
| |
| Authors: | Alicja Kowalska Andrzej Ma?lankiewicz Barbara Syrek Piotr Ciepliński |
| |
| Institution: | (1) Department of Organic Chemistry, Institute of Chemistry and Medical Physics, Silesian School of Medicine, PL-41-200 Sosnowiec, Poland |
| |
| Abstract: | The preparation of unsymmetrical 2,6-dialkoxy-7-methylpurines (2), and 2-alkoxy-1,7-dialkyl-6-oxo-1,6-dihydropurines (5) is described. In contrast to1 and2, a facile thermal lactim-lactam rearrangement from hypoxanthines5 and7 into xanthines6 was observed.
2,6-Dialkoxy-7-methylpurine Zusammenfassung Die Darstellung von unsymmetrischen 2,6-Dialkoxy-7-methylpurinen (2) und 2-Alkoxy-1,7-dialkyl-6-oxo-1,6-dihydropurinen (5) wird beschrieben. Im Gegensatz zu den Verbindungen1 und2 erfolgt die thermische Lactim-Lactam-Umlagerung der Hypoxanthine5 und7 zu den Xanthinen6 glatt. |
| |
| Keywords: | Nucleophilic heteroaromatic substitution Thermal lactim-lactam rearrangement [1 3] Sigmatropic shifts Dialkoxy-7H-purines Dialkyl-1H (or 3H) 7H-hypoxanthines Trialkyl-7H-xanthines) |
| 本文献已被 SpringerLink 等数据库收录！ |
|
