Simultaneous correlation chromatography,a new technique applied to calibration in high-performance liquid chromatography |
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Authors: | HC Smit C Mars JC Kraak |
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Institution: | Laboratory for Analytical Chemistry, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV Amsterdam The Netherlands |
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Abstract: | Simultaneous correlation chromatography (SCC) is introduced as a technique capable of analyzing several different samples simultaneously on the same chromatographic column. The theoretical basis of the technique is outlined and a computer simulation demonstrates the feasibility of the method. The advantages and potential of the technique are discussed. The technique is applied experimentally in a calibration procedure for high-performance liquid chromatography. During the calibration, unknown sample and calibration standards are processed under the same conditions, resulting in very accurate calibration. Other applications are outlined. |
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