Predicting retention data by target factor analysis and multiple regression analysis |
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Authors: | Darryl G Howery Gerald D Williams Nelson Ayala |
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Institution: | Department of Chemistry, The City University of New York, Brooklyn College, Brooklyn, NY 11210 U.S.A. |
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Abstract: | Target factor analysis is used to predict gas-chromatographic retention indices from a training-set data matrix for 13 solutes and 15 stationary phases. In the target-combination approach, sets of data vectors are target-tested in combination and the resulting coefficients for the best model are used for prediction. Retention indices for 42 solutes and 24 stationary phases are predicted to better than 1% even with a three-factor model. In the target free-float approach, values for missing retention indices on target test vectors are predicted. Predictions from sets of target-test data selected by chemical intuition are compared to those obtained from sets of target-test data selected by using models from the combination step. The target-combination approach and multiple-regression approach are overall of similar utility for predicting new data. |
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