两种铁剂治疗妊娠期缺铁性贫血疗效的研究

目的观察两种铁剂对妊娠期缺铁性贫血的治疗效果。方法80例缺铁性贫血孕妇随机分成两组，多糖铁组40例，每天早餐后给多糖铁复合物胶囊0．3g；多维铁组40例，多维铁口服溶液20mL／d分两次于早晚餐后服。主要观察指标：血红蛋白、平均红细胞容积、血清铁、铁蛋白等。结果两组治疗4周后，患者血红蛋白、平均红细胞容积及血清铁均有升高，且多糖铁组较多维铁组升高更明显，差异均有统计学意义（P〈0．05）。结论两种铁剂治疗妊娠期IDA均有效，多糖铁复合物胶囊升高血清铁效果显著，而且服用方便，患者用药依从性好，是治疗妊娠期缺铁性贫血理想的口服铁剂。

Study on the Curative Effect of Two Kinds of Iron Supplementation for Iron- deficiency Anaemia in Pregnancy

Objective To observe the curative effect of two kinds of iron supplementation to treat pregnant women with iron deficiency anemia （IDA）. Methods 40 pregnant women with IDA were treated with iron polysaccharide complex capsules （0. 3 g/d ） while another 40 pregnant women with IDA were treated with multivitamin iron oral solution （20 mL/d ）. Then hemoglobin （Hb）, mean corpuscular volume （MCV） , serum iron （Fe） , serum ferritin （SF） and adverse effect were observed both pre and post treatment respectively. Results After 4 weeks treatment, the Hb, MCV and serum iron in pregnant women with IDA who treated with iron polysaccharide complex capsules were increased more than those treated with multivitamin iron oral solution （P 〈 0.05 ）, and the ratio of adverse effect were rarely in both group. Conclusion Both iron polysaccharide complex capsules and multivitamin iron oral solution can treat pregnant women with IDA. The curative effect of iron polysaccharide complex capsules is good and its adverse effect is not significant, which is an excellent medicine to treat the disease.